Grey's Anatomy, the popular medical drama series, has been running for several years and has seen its fair share of on-set conflicts and feuds. This article explores the top 10 cast feuds that have occurred throughout the show's history.

The first feud mentioned is between Isaiah Washington, who played Dr. Preston Burke, and T.R. Knight, who portrayed Dr. George O'Malley. The tension between these two actors reportedly stemmed from an offensive remark made by Washington towards Knight on set, which eventually led to Washington's departure from the show.

Next on the list is the feud between Patrick Dempsey, who portrayed Dr. Derek Shepherd, and Isaiah Washington. This conflict began when Dempsey reportedly supported T.R. Knight after the offensive remark incident, further exacerbating the tensions between him and Washington.

Another notable feud mentioned in the article is between Katherine Heigl, who played Dr. Izzie Stevens, and Shonda Rhimes, the show's creator. Heigl publicly criticized the show's writing and declined to submit herself for Emmy consideration, which strained her relationship with Rhimes and ultimately led to her departure from the series.

Other feuds mentioned in the article include tensions between Katherine Heigl and co-star Ellen Pompeo, Patrick Dempsey and Eric Dane, Sandra Oh and Isaiah Washington, and more.

The article concludes by acknowledging that while these feuds may have caused disruptions behind the scenes, Grey's Anatomy has remained a successful and beloved show among fans. Despite the conflicts, the series has managed to maintain its popularity and longevity.